Free Treatment

Note from Selective Mutism Foundation, Inc.
Free treatment for Selective Mutism is included as an anxiety disorder.

STUDY:

Fluoxetine Treatment of Anxiety and Depression and Associated Brain Changes in Children and Adolescents Summary:
This study will determine if fluoxetine (Prozac®) is effective for treating anxiety or depression in children and adolescents.  The study will also use functional magnetic resonance imaging (fMRI) to learn more about how the brain functions in children/adolescents taking this medication for anxiety or depression.

Boys and girls ages 8 to 17 with anxiety and/or depression may be eligible for this outpatient treatment study.  Participants will first meet with a psychiatrist or psychologist for 2 weekly sessions of talk therapy.  Those who remain anxious or depressed after these 2 weeks will have the option of receiving treatment with fluoxetine daily for 8 weeks, or cognitive-behavioral therapy once a week for 8 weeks.  Parents also have the option of choosing a placebo for the 8 weeks. They will be seen by a doctor approximately weekly for 8 weeks to talk and complete verbal and written exercises.  Participants will be interviewed both individually and together with a parent to assess general mood, degree of nervousness, and behavior.

Those who have not improved by the end of the study will be offered other treatment for 1 to 3 months, and NIMH clinicians will help with finding subsequent aftercare.  Those who improve with treatment will continue therapy at NIMH until an outside physician is able to assume responsibility for monitoring the medication.

All procedures and medications associated with the research are provided at no cost to participants, and transportation expenses are reimbursed by NIMH.

Principal Investigator:
Daniel Pine, M.D.

For eligibility criteria and detailed information about this study: http://www.clinicaltrials.gov/ct/gui/show/ NCT00018057

To refer a patient, call NIMH:
301-496-5645